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January 3, 2008
By: Tim Wright
Editor-in-Chief, Contract Pharma
Addex Pharmaceuticals has entered an exclusive worldwide license agreement with Merck to develop ADX63365, an oral drug candidate for the potential treatment of schizophrenia and other undisclosed indications. ADX63365, currently in preclinical development, is a positive allosteric modulator (PAM)—a new class of therapeutic agents—that targets the metabotropic glutamate receptor 5 (mGluR5), which is believed to be an important target for the treatment of schizophrenia and other conditions. The a...
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